Emtrim Suspension 240mg is a pediatric antibiotic formulation containing the combination of sulfamethoxazole and trimethoprim. This dual-action suspension provides comprehensive antimicrobial coverage for treating various bacterial infections in children. Emtrim Suspension features a palatable flavor to improve compliance and comes in a precisely calibrated liquid form for accurate pediatric dosing.
Uses
Emtrim Suspension treats a variety of bacterial infections in children including urinary tract infections, middle ear infections (otitis media), bronchitis, and certain types of pneumonia. It’s also effective against specific gastrointestinal infections and is sometimes prescribed for prophylaxis against certain infections in immunocompromised children.
Benefits
- Broad-spectrum antibacterial activity against many pathogens
- Synergistic action targets bacterial metabolism at two different points
- Lower resistance development compared to single-agent antibiotics
- Convenient liquid formulation for precise pediatric dosing
- Palatable flavor improves medication adherence
- Effective against both gram-positive and gram-negative bacteria
- Reduced treatment duration for many common infections
- Cost-effective treatment option
- Available in child-friendly suspension form
How It Works
Emtrim Suspension works through a dual mechanism of action. Sulfamethoxazole inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the enzyme dihydrofolate reductase. This sequential blockade of two enzymes in the bacterial folate synthesis pathway creates a synergistic effect.
Duration of Action
Emtrim Suspension begins working within 1-2 hours after administration. Peak blood levels occur approximately 4 hours after dosing. The therapeutic effect generally lasts 12 hours, which supports twice-daily dosing. Complete treatment courses typically range from 5-14 days depending on the infection being treated.
Dosage
Age Group | Standard Dose | Frequency |
---|---|---|
6 months-5 years | 5ml | Every 12 hours |
6-12 years | 10ml | Every 12 hours |
Severe infections | Weight-based | Every 12 hours |
Side Effects
Common side effects of Emtrim Suspension may include mild nausea, vomiting, loss of appetite, or temporary taste disturbances. Less common effects include mild skin rash, itching, or photosensitivity. Severe side effects requiring immediate medical attention include persistent fever, sore throat, unusual bleeding/bruising, or yellowing of eyes/skin.
Warning
Discontinue Emtrim Suspension and seek immediate medical attention if signs of serious allergic reactions occur (rash, itching/swelling, severe dizziness, trouble breathing). Prolonged use may result in oral thrush, secondary infections, or bacterial resistance. Complete the full prescribed course even if symptoms improve before completion.
Pregnancy and Breastfeeding
Emtrim Suspension is not typically prescribed to pregnant or breastfeeding individuals as this is a pediatric formulation. For adolescent females who might be pregnant, Emtrim should be avoided, particularly during the first trimester and near term, as it may cause birth defects or jaundice in newborns.
Interactions
- May increase effects of oral anticoagulants
- Could raise blood levels of phenytoin and other anticonvulsants
- Potential interaction with methotrexate, increasing toxicity risk
- May interfere with certain diabetes medications
Precautions
Maintain adequate fluid intake while taking Emtrim Suspension to prevent crystalluria. Avoid prolonged sun exposure due to increased photosensitivity risk. Store medication away from direct light at room temperature. Shake well before each use to ensure proper drug distribution and accurate dosing.
Important Information
Emtrim Suspension contains sulfamethoxazole and should not be used in children with sulfa allergies. Complete the entire prescribed course even if symptoms improve. Measure doses carefully using the provided measuring device. Report any unusual symptoms promptly to your healthcare provider. Keep Emtrim Suspension refrigerated after reconstitution if directed. Discard unused medication after the specified period.
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